Dr. Umesh Srikantha

Areas of Expertise

• Minimally Invasive Spine Surgery
• Complex spine surgery
• Endoscopic Spine surgery

Educational Qualification

• Dr. Umesh Srikantha did his MBBS from Karnataka Institute of Medical Sciences, Hubli, Karnataka.
• Pursued M.Ch training in Neurosurgery from the National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka.
• Pursued his training by doing a Fellowship in Minimally Invasive Spine Surgery at Nanoori Hospital, Incheon, South Korea, under Dr. Seungcheol Lee.
• Trained in stereotactic and functional neurosurgery and neuro-oncology.
• Pursued numerous international courses within his field:
  • Advanced LIF course SICOT lab, Bangkok, Thailand.
  • O-arm Surgical Synergy course, Seoul, South Korea.
  • Hemostasis and sealing in Spine Surgery, Minimally Invasive Surgical Skills Center, Hong Kong.
  • First Navigated 3-D ultrasound (SONOWAND) hands-on course, Bratislava, Slovakia.
  • Advanced course in degenerative spine surgery, Seoul, South Korea.

Work Experience

• Dr. Umesh Srikantha has rich experience performing nearly 2000 Minimally Invasive spine procedures and more than 4,500 procedures in the brain and spine overall.
• His experience in MISS ranges from basic procedures like micro lumbar discectomy, foraminotomy and decompression surgeries to the most complex spinal fusion procedures for advanced pathologies like tumours, multi-level cervical spondylotic myelopathy and high-grade spondylolisthesis.
• Assistant and Associate Professor at M S Ramaiah Medical College and Hospital, Bangalore, India. (May 2009 to April 2016)
• Senior Resident, Department of Neurosurgery, NIMHANS, Bangalore (Sept. 2006 to May 2009)

Languages Spoken

• English
• Kannada
• Hindi

Offering Spine Specialist Services at

• Hebbal, Sahakara Nagar, Bengaluru, Karnataka
• J. P. Nagar, Bengaluru, Karnataka

Membership

• Neurological Society of India - NSI
• Bangalore Neurological Society – BNS
• Indian Medical Association – IMA (Bangalore)
• Minimally Invasive Spine Surgeons Association of Bharat (MISSAB)
• Association of Spine Surgeons of India (ASSI)
• Neuro-spinal Surgeons Association (NSSA)
• Skull Base Surgery Society of India (SBSSI)

Awards

• Silver jubilee award for the ‘Best Outgoing Student’ from NIMHANS, Bangalore, one of the premier institutes for neurosurgery training in the country.

Achievements

• Trained more than 100 aspiring surgeons to adopt MISS through more than 40 advanced training programs of different formats.
• Presented his advanced MISS cases at a number of conferences.
• Been a part of several research projects on brain tumours as well.
• Invited faculty for several workshops and conferences on minimally invasive spine surgery.
• Conducted several cadaveric hands-on training courses and trained more than 100 surgeons from all over the country on minimally invasive spine surgery.
• More than 20 publications in renowned national and international journals and authored book chapters on Minimally Invasive Spine Surgery.
• Pioneering cadaver capsule courses on minimally invasive spine surgery for the cervical spine and cranio-vertebral junction, on OLIF and MIS-TLIF, MAST decompression and PPF, Posterior Cervical Instrumentation which has been successfully applied into clinical practice.

Research

• Dr. Umesh Srikantha served as a co-investigator in a multinational, multicenter study designed to assess the effectiveness of a novel drug, AP12009—now known as Trabedersen. This drug, a TGF-β2 antisense phosphorothioate oligonucleotide inhibitor of TGF-β2, was evaluated in adult patients with recurrent high-grade gliomas. The research was conducted under the title: "A multi-national, multi-centre, open-label, active-controlled, randomised parallel-group dose-finding study to evaluate the efficacy and safety of two doses of AP 12009, administered intratumorally as continuous high-flow microperfusion over 7 days every other week." The study received funding from Anti-sense Pharma, Germany, and coordination in India was managed by SIRO Clinpharm Pvt. Ltd, Mumbai. Our centre, NIMHANS in Bangalore, contributed 14 test subjects to the study.
• Dr. Umesh Srikantha participated in a multi-institutional project titled “A prospective study to correlate gene signatures with clinical outcomes of astrocytomas and identification of potential therapeutic target(s) in glioblastoma.” This research was supported by the Council for Scientific and Industrial Research (CSIR), Government of India. The findings contributed to several publications on glioblastoma biomarkers in esteemed peer-reviewed cancer journals, including 'Clinical Cancer Research' and 'Cancer Biology and Therapy'.
• Dr. Umesh Srikantha contributed to a study focused on evaluating the clinical and histological features, as well as the expression of immunohistochemical markers in medulloblastoma with an aim to correlate these aspects with recurrence rates. The study identified the most critical predictors of recurrence as the extent of resection, use of chemotherapy, presence of gross anaplasia, and overexpression of c-erb B2. These factors were integrated into a 'clinical-histological-immunohistochemical' model for medulloblastoma. The findings from this study were submitted to NIMHANS and published in the British Journal of Neurosurgery.

Publications

Books & Chapters Published

• 8 chapters in Pai Neurosurgical Atlas
• Chapter in Sagittal Balance of the Spine, NSI.

National & International Journal Publications

• Minimally Invasive Spine Surgery Enabling the Feasibility of Single-stage Surgery for Tandem Spinal Stenosis. Published in Journal of Spinal Surgery. 2023 Apr 1;10(2):61-5.
• A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism. Published in Journal of Craniovertebral Junction & Spine. 2023 Jan;14(1):97.
• Interlaminar full-endoscopic discectomy for L5-S1 disc herniations: Surgical technique and early outcomes during the learning curve. Published in Journal of Spinal Surgery. 2022 Oct 1;9(4):205-11.
• The current status and surgical outcome of the minimally invasive techniques for lumbar interbody fusion in India: A systematic review and meta-analysis. Published in Journal of Craniovertebral Junction & Spine. 2022 Jul;13(3):245.
• Delayed C5 palsy following anterior cervical discectomy and arthroplasty – Rare presentation of two cases by an unusual phenomenon of “flosealoma”. Published in Journal of Spine Surgery 2022;9(2):128-33.
• MIS-TLIF: Technical Note, Learning Goals behind Case Selection during Early Part of Learning Curve and Clinical Outcomes in First 150 Cases. Published in Journal of Clinical Orthopaedics Jan-Jun 2022;7(1):85-93.
• Minimally Invasive Iliac Screw Insertion: Clinical case series and Technical Note. Published in Journal of Minimally Invasive Spine Surgery and Technique 2022;7(1):60-67
• Tube-assisted Minimally Invasive versus Open Posterior decompression for multilevel Degenerative Cervical Myelopathy – A Prospective Comparative Study. Published in Journal of Minimally Invasive Spine Surgery and Technique 2022;7(1):16-27
• Minimally invasive subaxial cervical pedicle screw placement with routine fluoroscopy: cadaveric feasibility study and report of 6 clinical cases. Published in Journal of Minimally Invasive Spine Surgery and Technique 2022;7(1):98-106
• Minimally Invasive cervical Laminoforaminotomy – Technique and outcomes. Published in Journal of Craniovertebral Junction and Spine 2021;12:361-7
• Rare Case of a Solitary Spinal Osteochondroma with Myelopathy Treated by a Minimally Invasive Technique. Published in Backbone 2021 2(2) Oct-Mar 98-101. DOI:10.13107/bbj.2022.v02i02.029
• Posterior Cervical Fixation techniques after Laminectomy. In Zileli M, Parthiban J (Eds.), Cervical Spondylotic Myelopahty and Ossification of Posterior Longitudinal Ligament- Published in WFNS committee book. 219-235. Thieme publishers.
• Complete Excision of Intradural-Extraforaminal Spinal Tumors Using a Minimally Invasive 2-Incision Technique with Fixed Tubular Retractors. Published in Clinical Spine Surgery 2021 Apr 1;34(3):92-102. doi: 10.1097/BSD.0000000000001036. PMID: 32694469.
• Minimal Invasive Transforaminal Lumbar Interbody Fusion for Isthmic Spondylolisthesis with Nerve Root Anomaly in Young Adult Male Football Player: Case Report. Published in Backbone. 2021 Apr-Sep;2(1):43-47.
• Minimally Invasive Spine Surgery. Part-2: Tumour, Trauma, Infection and Radiation Exposure. Published in Current Practice in Neurosciences. 2020 Sep;2(5):1-17.
• Syringo-Subarachnoid Shunt Placement: A Minimally Invasive Technique Using Fixed Tubular Retractors-Three Case Reports and Literature Review. Published in The International Journal of Spine Surgery (IJSS). 2020 Apr 30;14(2):133-139. doi: 10.14444/7020. PMID: 32355617; PMCID: PMC7188106.
• Minimally Invasive Spine surgery. Published in Progress in Clinical Neurosciences (Vol 33) ed. Panikar D, Tripathi M. Thieme Medical and Scientific Publishers Pvt. Ltd. 2019;33:87-98.
• Unilateral Laminotomy and Bilateral Decompression for Lumbar canal stenosis. Published in Progress in Clinical Neurosciences (Vol 33) ed. Panikar D, Tripathi M. Thieme Medical and Scientific Publishers Pvt. Ltd. 2019;33:99-110.
• Minimally Invasive Spine surgery – A ready reckoner. Published in Neurology India 2019;67:959-60
• Minimally invasive lateral transpsoas approach for lumbar corpectomy and stabilization. Published in Surgical Neurology International 2019 Aug 2;10:153
• Supraorbital Craniotomy for Large Anterior Skull Base Meningiomas: A Technical Note. Published in Asian Journal of Neurosurgery, 2019 Jul-Sep;14(3):767-772.
• Rare manifestation of common disease with an unique method of minimally invasive spine stabilization: Cervical 2-3 facet lesion. Published in Journal of Craniovertebral Junction and Spine. 2018 Jul-Sep ;9(3):209-211.
• Giant posterior fossa dural cavernoma in a child. Published in Child's Nervous System, 2017 Apr;33(4):691-694.
• Minimally invasive Atlanto-axial fusion: Cadaveric study and report of 5 clinical cases. Published in Journal of Neurosurgery: Spine 2016 Dec;25(6):675-680. Epub 2016 Jul 15.
• Managing a Rare Malignant Sweat Gland Tumor Invading the Brain: Case Report and Literature Review. Published in World Neurosurgery 2016;86:513.e1-7 (https://www.sciencedirect.com/science/article/abs/pii/S187887501501205X?via%3Dihub)
• Pediatric calcified intramedullary schwannoma at conus: A common tumor in a vicarious location. Published in Journal of Pediatric Neurosciences. 2016 Oct-Dec; 11(4): 319–321. doi: 10.4103/1817-1745.199474
• Surgical management of Giant Lumbar Extradural Schwannoma: Report of 3 cases. Published in International Journal of Spine Surgery 2015;9:18 (doi: 10.14444/2018)
• Spinous Process splitting Laminectomy: Clinical outcome and Radiological analysis of extent of decompression. Published in International Journal of Spine Surgery 2015;9:20 (doi: 10.14444/2020)
• Two children with Split cord malformation. Published in Pediatric Neurology Journal 2015;53(5):468-9. DOI: http://dx.doi.org/10.1016/j.pediatrneurol.2015.03.021
• Minimally Invasive vs Open Transforaminal Lumbar Interbody Fusion - Early outcome observations. Published in Journal of Spinal Surgery 2014;2(1):1-7
• Posterior Cervical Laminoforaminotomy: A Comparative study between Open vs Minimally Invasive approach. Published in Journal of Spinal Surgery 2014;2(1):8-12.
• Lee SC, Kang JH, Srikantha U, Jang IT, Oh SH. Extraforaminal compression of L5 nerve root at the lumbo-sacral junction: Clinical analysis, Technique of decompression and Outcome. J Neurosurg Spine. Published online January 24, 2014; DOI: 10.3171/2013.12.SPINE12629
• Srikantha U, Khanapure K, Nirmala S, Varma RG. Occipital dermal sinus with a vermian dermoid. J Neurosci Rural Pract 2012;3:392-4
• Umesh Srikantha, Kiran Khanapure, Murali Mohan S, Ravi Gopal Varma. Sphenoidal ectopic ACTH-secreting Pituitary adenoma. J Pioneering Med Sci 2012;2(2) (Apr-Jun) (online).
• Madhugiri VS, Sastri BV, Srikantha U, Banerjee AD, Somanna S, Devi BI, Chandramouli BA, Pandey P. Focal intradural brain infections in children: An analysis of management and outcome. Pediatric Neurosurgery 2011;47(2):113-24
• Umesh Srikantha, Anandh Balasubramaniam, Vani Santosh, Sampath S, Indira Devi B, Chandramouli BA. Recurrence in medulloblastoma – Influence of clinical, histological and immunohistochemical factors. British Journal of Neurosurgery 24(3):280-288, 2010.
• Umesh S, Tandon A, Santosh V, Anandh B, Sampath S, Chandramouli BA, Sastry KVR. Clinical and immunohistochemical prognostic factors in adult glioblastoma patients. Clin Neuropathol 28(5):362-72, 2009.
• Umesh Srikantha, Jagadeesh V Morab, Savitr Sastry, Rojin Abraham, Anandh Balasubramaniam, Sampath Somanna, Indira Devi, Chandramouli BA, Paritosh Pandey. Outcome of Ventriculo-Peritoneal Shunt in Grade IV Tubercular Meningitis with Hydrocephalus- A retrospective analysis of 95 patients. J Neurosurg Pediatrics 4:176-183, 2009.
• Reddy PS, Umesh S, Thota B, Tandon A, Pandey P, Hegde AS, Balasubramaniam A, Chandramouli BA, Santosh V, Rao MR, Kondaiah P, Somasundaram K. PBEF1/NAmPRTase/Visfatin: a potential malignant astrocytoma/glioblastoma serum marker with prognostic value. Cancer Biol Ther. 2008 May;7(5):663-8.
• Umesh Srikantha, Indira Devi Bhagavatula, Satish Satyanarayana, Sampath Somanna, Bengaluru A Chandramouli. Spinal osteochondroma: spectrum of a rare disease. J Neurosurg Spine. 2008 Jun ;8 (6):561-566.
• Reddy SP, Britto R, Vinnakota K, Aparna H, Sreepathi HK, Thota B, Kumari A, Shilpa BM, Vrinda M, Umesh S, Samuel C, Shetty M, Tandon A, Pandey P, Hegde S, Hegde AS, Balasubramaniam A, Chandramouli BA, Santosh V, Kondaiah P, Somasundaram K, Rao MR. Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis. Clin Cancer Res. 2008 May 15;14(10):2978-87.
• Britto R, Umesh S, Hegde AS, Hegde S, Santosh V, Chandramouli BA, Somasundaram K. Shift in AP-2alpha localization characterizes astrocytoma progression. Cancer Biol Ther. 2007 Mar;6(3):413-8.
• Pandey P, Umesh S, Bhat D, Srinivas D, Abraham R, Pillai S, Balasubramaniam A, Devi I, Sampath S, Chandramouli BA. Cerebellar abscesses in children: excision or aspiration. 1: J Neurosurg Pediatrics. 2008 Jan;1(1):31-4.